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Joint Contractures, Ulcerations, Severe Raynaud’s Linked to Impaired Hand Function in Scleroderma

The presence of moderate or severe small joint contractures, finger ulcerations, and the severity of Raynaud’s phenomenon show the strongest association with impaired hand function in scleroderma patients, a study reports. The study, “The association of sociodemographic and disease variables with hand function: a Scleroderma Patient-centered Intervention Network cohort…

Stem Cell Transplant Benefits in People with Severe Systemic Disease Can Be Long-lasting, Trial Extension Data Show

Stem cell transplant confers superior and long-lasting clinical benefits compared to conventional treatment with Cytoxan cyclophosphamide in people with severe systemic scleroderma, including better functional ability and disease control, and prolonged survival, long-term extension data from a Phase 2/3 clinical trial show. The study, “…

New US Patent Protects Corbus’ Scleroderma Therapy Until 2034

The U.S. Patent and Trademark Office (USPTO) has issued a new patent to Corbus Pharmaceuticals to cover the use of investigational lenabasum-based therapies for the treatment of fibrotic diseases, including scleroderma. The patent, No. 10,085,964, provides the company exclusive rights for the use of lenabasum-based pharmaceutical compositions…