Author Archives: Ashraf Malhas, PhD

Scleroderma Patients with Gastrointestinal Involvement Have Unique Microbiota Profile

A study of the gut bacterial composition in scleroderma patients identified unique bacterial alterations associated with clinical evidence of gastrointestinal disease. Many patients with scleroderma, also known as systemic sclerosis (SSc), suffer from gastrointestinal tract symptoms, with almost all of those with longstanding disease having upper gastrointestinal involvement. Focus has recently shifted…

Mycophenolate Mofetil Is Effective Therapy for Scleroderma-related Lung Disease, Study Confirms

Mycophenolate mofetil stabilizes the lung function of patients with systemic sclerosis-associated interstitial lung disease, or SSc-ILD, a study confirms. The stabilization occurs even when the therapy, whose short name is MMF, is administered in doses lower than those used in a previous Phase 2 clinical trial. The latest study is retrospective, which…