Posts by: Patricia Inacio, PhD

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High levels of a protein called KL-6, produced by lung cells and secreted into the blood, can predict early signs of lung function worsening in patients with systemic sclerosis-related ... Read more

May 8, 2018May 8, 2018

Levels of Specific Cytokines Linked to Clinical Manifestations of Scleroderma, Study Reports

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Levels of certain important signaling molecules called cytokines are associated with different clinical manifestations in patients with scleroderma, a study suggests. The study, “Different profile of cytokine production in ... Read more

April 12, 2018April 12, 2018

Therapeutic Plasma Exchange Appears to Treat SSc, But Clinical Trial Needed, Study Says

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Therapeutic plasma exchange, which aims to treat systemic sclerosis (SSc) by clearing the blood of antibodies, cytokines and other factors that might promote disease progression, shows potential as a ... Read more

March 29, 2018March 29, 2018

Nutritional Screening Needed to Identify SSc Patients at Risk of Malnutrition, Study Says

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Severe malnutrition significantly decreases the quality of life of patients with systemic sclerosis (SSc), according to researchers. Standardized nutritional screening is needed to identify those at risk of malnutrition ... Read more

March 6, 2018March 7, 2018

Half of Britons with Rare Rheumatic Disease Need Three Years for Diagnosis, Report Says

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It takes more than three years for half of Britons with rheumatic diseases like scleroderma, lupus and vasculitis to obtain a correct diagnosis, according to a Rare Autoimmune Rheumatic Diseases ... Read more

March 1, 2018March 1, 2018

Fat Tissue Cell Therapy Improves Scleroderma Patients’ Hand Function, Trial Shows

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Implanting some of scleroderma patients’ fat cells in their fingers significantly improved their hand function and overall disability, a clinical trial showed. The STAR trial (NCT02396238) dealt with Cytori ... Read more

February 8, 2018February 8, 2018

Myeloablative Stem Cell Transplant Improves Long-term Outcomes in Severe Scleroderma, Trial Shows

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Immunosuppressive therapy followed by an autologous stem cell transplant resulted in significant long-term benefits, including improved overall survival, in adult scleroderma patients compared to immunosuppressive therapy alone, according to ... Read more

January 30, 2018January 30, 2018

Macrophages May Promote Progression of Systemic Sclerosis, Study Shows

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New research establishes a link between immune cells, known as macrophages, and systemic sclerosis progression. The study showed that gene expression in macrophages from systemic sclerosis patients is altered, ... Read more

December 5, 2017December 5, 2017

Newly ID’d Gene Variant Linked to Slower Progression of Systemic Sclerosis in Women in Small Study

News

A newly discovered genetic variant in the FOXP3 gene is associated with a slower progression of systemic sclerosis in women, a small Italian cohort study reports. The research “FOXP3, ... Read more

November 9, 2017November 9, 2017

75% of Scleroderma Patients Show Meaningful Skin Improvement with Anabasum, Extension Study Shows

News

The thick skin that is a hallmark of scleroderma showed meaningful improvement in 75 percent of patients treated with Corbus Pharmaceuticals’ anabasum (JBT-101), according to initial results of an extension trial. ... Read more

Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

KL-6 Protein Can Predict Early Lung Worsening in Systemic Sclerosis with ILD, Study Says

Levels of Specific Cytokines Linked to Clinical Manifestations of Scleroderma, Study Reports

Therapeutic Plasma Exchange Appears to Treat SSc, But Clinical Trial Needed, Study Says

Nutritional Screening Needed to Identify SSc Patients at Risk of Malnutrition, Study Says

Half of Britons with Rare Rheumatic Disease Need Three Years for Diagnosis, Report Says

Fat Tissue Cell Therapy Improves Scleroderma Patients’ Hand Function, Trial Shows

Myeloablative Stem Cell Transplant Improves Long-term Outcomes in Severe Scleroderma, Trial Shows

Macrophages May Promote Progression of Systemic Sclerosis, Study Shows

Newly ID’d Gene Variant Linked to Slower Progression of Systemic Sclerosis in Women in Small Study

75% of Scleroderma Patients Show Meaningful Skin Improvement with Anabasum, Extension Study Shows

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