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What is it like living with scleroderma? This video takes a look at some of the struggles that patients face when dealing with this life altering autoimmune disease. The video features actor, Jason Alexander; Football Hall of Famer, Barry Sanders; Actor and Comedian, Mark Teich; Author and Personality,…

In a new research paper, scientists at the Faculty of Dentistry, Aristotle University of Thessaloniki, Greece, presented a clinical report of a systemic sclerosis case where the jaw was affected. The research paper, whose goal is to raise awareness among oral radiologists and other health professionals, is entitled “…

In a new study entitled “Systemic Sclerosis Patients Present Alterations in the Expression of Molecules Involved in B-Cell Regulation,” a team of researchers investigated whether patients with systemic sclerosis present changes in their immune B cells profile (including frequency and activation phenotypes), focusing particularly on the B…

iBio, Inc., a plant-based biotechnology company focused on developing biological therapies for several fibrotic diseases including idiopathic pulmonary fibrosis and systemic sclerosis, recently announced it has received a notification from the European Patent Office stating that the opposition period for the iBio patent 2192172, entitled “System for Expression of…

Reata Pharmaceuticals, Inc., a biopharmaceutical company based in Irving, Texas, recently announced positive data from the Phase 2 clinical trial LARIAT assessing the company’s candidate product bardoxolone methyl for pulmonary arterial hypertension (PAH). The results were recently presented by Dr. Ronald Oudiz, Director of the Pulmonary Hypertension Center and…

Cytori Therapeutics, Inc., a company focused on therapeutics and devices in the field of regenerative medicine, recently reported it has enrolled and administered treatment to the first patient in its ongoing SCLERADEC-II trial, a late phase, follow-on European study that aims to evaluate the efficacy and safety profile of Cytori…

A recent study identified a novel molecule implicated in the development of skin fibrosis, a serious disease characterized by the inflammation and hardening of skin tissue. The study entitled “The matrix protein Fibulin-5 lies at the interface of tissue stiffness and inflammation in fibrosis” was recently published…

In a recent study entitled “Molecular network of important genes for systemic sclerosis-related progressive lung fibrosis”, published in the BMC Research Notes journal, a team of researchers from the US and China established the expression levels of crucial genes for Systemic Sclerosis-related progressive pulmonary…

This week at the Scleroderma Foundation of Southern California’s 17th annual “Key to a Cure” gala, Genentech‘s Senior Group Medical Director of Immunology, Dr. Jeffrey Siegel, will receive the honor of the Spirit of Leadership Award. The award is given to prominent individuals who have contributed to the scientific and…

In a recent study entitled “B regulatory cells are decreased and functionally impaired in patients with systemic sclerosis”, researchers report that a specific population of B cells – regulatory B cells – with established functions in immune suppression, have their numbers markedly reduced and functions impaired in systemic…