News

The European Commission has granted late stage cell therapy company Cytori Therapeutics, Inc.’s ECCS-50 cellular therapy the designation of orphan medicinal product for the treatment of scleroderma. The decision, which was made due to positive references from the European Medicines Agency’s (EMA) Committee for Orphan Medicinal Products, represents the first time an…

A study recently published in the on-line journal Clinical and Experimental Rheumatology is challenging the clinical assumptions that morphea and systemic sclerosis (SSc) should be considered the part of the same disease spectrum.  The study, entitled, “Prospective evaluation of frequency of signs of systemic sclerosis…

Results from a recent study published in the journal The Egyptian Rheumatologist provide new evidence of inner ear involvement in Systemic sclerosis (SSc) causing audiovestibular abnormalities. Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by fibrosis mainly in the skin, vasculopathy with…

A recent Case Report entitled “Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis,” describes a rare case of a patient with Posterior Reversible Encephalopathy Syndrome (PRES) caused by arterial hypertension and very early systemic sclerosis (SSc). The report is published in…

Researchers at Centro Universitário Augusto Motta and Hospital Federal de Bonsucesso in Rio de Janeiro, Brazil recently discovered that muscle strength in the lower limbs of patients with systemic sclerosis influences the patient’s functional capacity and quality of life. The study is entitled “Lower…

Researchers from the University of Cologne in Germany showed that Systemic sclerosis-overlap Syndrome should be regarded as different separate subset in Systemic sclerosis (SSc) patients. The study entitled “Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis” appeared on…

A recent study published in the journal PLOS One reports the results of a comprehensive clinical assessment review in patients with Systemic sclerosis and lung cancer. Systemic sclerosis (SSc) is a connective tissue disorder characterized by immune dysregulation and accumulation of extracellular matrix constituents resulting in…

A case study of a patient with Scleroderma recently published in the journal JAAD Case Reports reports the clinical outcomes of treatment with HDAC (Histone deacetylase inhibition) with divalproex sodium. Scleroderma is a complex autoimmune connective tissue disease, and although the causes remain unclear, research suggests that transforming growth…

Researchers from the Hunter Holmes McGuire VA Medical Center, Richmond, VA, and the Department of Rheumatic and Immunologic Diseases, Orthopedics and Rheumatology Institute, Cleveland Clinic, OH, have recently released results from a clinical trial that evaluated the use of ambrisentan, a selective endothelin type A receptor antagonist,…

The Assistance Publique – Hôpitaux de Paris is collaborating with Actelion Pharmaceutics on a study testing the efficacy, safety and tolerability of bosentan in patients with scleroderma renal crisis on renal function (ClinicalTrials.gov Identifier: NCT01241383). Systemic sclerosis (SSc) is an auto-immune disorder that causes excessive collagen deposition,…