News

A new collaboration between Servier Pharmaceuticals and University College London (UCL) seeks to speed the discovery of new therapies for immune-inflammatory disorders such as scleroderma. The initial two-year agreement calls for Servier to share scientific knowledge with UCL researchers who are investigating how scleroderma develops, as well as…

The Scleroderma Foundation is among the recipients of nearly $200,000 in awards through the 2020 RARE Patient Impact Grant program of Global Genes, a rare disease patient advocacy organization. Twenty foundations will receive funding to improve the lives of rare disease patients through education, resources, and other support.

Cedars-Sinai has received a $20-million donation from Dr. and Mrs. Min H. Kao and the Kao Family Foundation to establish the Kao Autoimmunity Institute to foster research and find treatments for rheumatic disorders. The donation will also help launch the institute’s Scleroderma Program, which is designed to provide…

About a third of people diagnosed with scleroderma in the U.S. were prescribed immunosuppressive therapies in the first year after their diagnosis, but their symptoms were found to be similar to those of other scleroderma patients — possibly indicating the low efficacy of these treatments, a study…

Cantargia will start the preclinical development of a new antibody, called CAN10, intended to treat people with scleroderma and myocarditis. The company aims to launch a Phase 1 clinical trial in late 2021. CAN10 was designed to specifically block the activity of the interleukin 1…

A Phase 2a clinical trial designed to test Galapagos‘ investigational oral therapy GLPG1690 in people with diffuse cutaneous scleroderma has completed enrolling participants, the company announced. GLPG1690 is a small molecule that targets and blocks autotaxin. This enzyme…

Despite skyrocketing healthcare costs, President Trump is committed to protecting the 30 million or so Americans with rare diseases and ensuring timely, affordable access to lifesaving treatments, the nation’s highest-ranking health official said. “We have to think about how our financing system can protect those with serious and rare illnesses.

Bob Saget will host the 42nd annual “Cool Comedy — Hot Cuisine” benefit of the Scleroderma Research Foundation (SRF) on Tuesday, Dec. 10. Saget, a well-known actor and a board member of SRF, will be joined by fellow comedians Michael Che, Jim Gaffigan and…

A single dose of an engineered antibody known as CD45-ADC can effectively eliminate disease-causing immune cells and ease the symptoms of scleroderma in mice, studies show. CD45-ADC is an example of Magenta Therapeutics‘ efforts to develop targeted antibody-drug conjugates (ADCs) to specifically remove disease-causing cells from the…

Health Canada has approved Ofev (nintedanib) as a treatment to slow the decline of pulmonary function in people with scleroderma-associated interstitial lung disease (SSc-ILD). The approval makes Ofev, by Boehringer Ingelheim, the first treatment for people with SSc-ILD available in Canada. It follows the therapy’s recent approval in the…