Author Archives: Marta Figueiredo PhD

EnZen Invests in Thirona to Help Develop Topical Fibrosis Therapy

Thirona Bio has partnered with EnZen Therapeutics to accelerate the development of its experimental topical therapy FBM5712 for scleroderma and other conditions associated with scarring (fibrosis). EnZen’s investment in Thirona, part of a convertible promissory note arrangement, may be converted into equity in the long run. The companies…

Stem Cell-derived Tiny Vesicles Lessened Fibrosis, Inflammation

Under-the-skin treatment with tiny vesicles produced by mesenchymal stem cells significantly lessened skin abnormalities and scarring, while reducing markers of disease and inflammation, in a mouse model of scleroderma, a study showed. Notably, these beneficial effects — similar to those of treatment with the bone marrow-derived mesenchymal stem cells…

Group Sessions Helpful for Mild Anxiety During COVID-19, Trial Finds

A remote, peer-facilitated group intervention created to provide mental health and social support during the COVID-19 pandemic significantly eased anxiety and depression in adults with systemic scleroderma and mild anxiety, according to data from the SPIN-CHAT trial. Differences between the group of patients who underwent the one-month intervention…