Posts by: Jose Marques Lopes, PhD

News

Patients with scleroderma and pulmonary arterial hypertension (PAH) have increased levels of two serum proteins, midkine (MDK) and follistatin-like 3 (FSTL3), according to a new study. The finding indicates ... Read more

August 9, 2018August 9, 2018

Lupus Overlap in Scleroderma Patients Does Not Seem to Affect Survival, Study Shows

News

Patients with both scleroderma and systemic lupus erythematosus (SLE) are younger at diagnosis, are more often women, and have less skin manifestations, but most importantly, show similar survival rates ... Read more

August 7, 2018August 7, 2018

HMGB1 Protein May Drive Blood Vessel, Tissue Damage in Scleroderma, Study Suggests

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A protein involved in inflammation and tissue regrowth — HMGB1 — may be the main driver of blood vessel damage and tissue fibrosis in scleroderma, suggesting its potential as ... Read more

July 24, 2018July 24, 2018

Innate Immunity Protein a Potential Therapeutic Target in Scleroderma, Study Suggests

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A key innate immunity protein called TLR4 is a key driver of organ fibrosis, according to a new study conducted in mice and scleroderma patients. The finding suggests that ... Read more

June 7, 2018June 7, 2018

Opsumit and Esbriet Combo Improves Scleroderma-related Interstitial Pneumonia and PAH, Case Report Shows

News

Treatment with Opsumit (macitentan) and Esbriet (pirfenidone) provided stable improvements in a scleroderma patient with interstitial pneumonia and borderline pulmonary arterial hypertension (PAH), according to a Japanese case report. The ... Read more

April 19, 2018April 19, 2018

Venous Blood Clots Do Not Increase Mortality in Scleroderma Patients, Study Shows

News

The occurrence of blood clots in the veins of scleroderma patients is rare and does not change patients’ survival rates, a new Canadian study shows. Still, researchers see a need ... Read more

April 17, 2018April 17, 2018

Interstitial Lung Disease Associated with Greater Risk of Lung Cancer in Scleroderma, Study Reports

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Having interstitial lung disease (ILD) is associated with a greater risk of lung cancer in scleroderma patients, according to Canadian researchers. Their findings also demonstrate that male sex and ... Read more

March 27, 2018March 27, 2018

Nailfold Capillary Damage a Mortality Predictor in Scleroderma, Study Shows

News

Nailfold capillary damage was found to be a predictor of mortality in scleroderma patients, according to researchers from Australia. The study, “The role of Nailfold Capillary Dropout on Mortality ... Read more

March 22, 2018March 22, 2018

Scleroderma Foundation Among Supporters to Improve Michigan Patients’ Access to Medications

News

Major healthcare organizations are throwing their support behind an initiative called “Let MI Doctors Decide” intended to improve patient access to prescribed medicines for scleroderma and other autoimmune disorders ... Read more

October 5, 2017October 5, 2017

Innate Immune System and MicroRNA Play Crucial Roles in Scleroderma Development, Study Suggests

News

The innate immune system and small RNA molecules known as microRNA are key factors in the development of scleroderma, according to a study based on previously published research. The ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

Combined Measurement of 2 New Serum Biomarkers May Speed Diagnosis of SSc-PAH Patients

Lupus Overlap in Scleroderma Patients Does Not Seem to Affect Survival, Study Shows

HMGB1 Protein May Drive Blood Vessel, Tissue Damage in Scleroderma, Study Suggests

Innate Immunity Protein a Potential Therapeutic Target in Scleroderma, Study Suggests

Opsumit and Esbriet Combo Improves Scleroderma-related Interstitial Pneumonia and PAH, Case Report Shows

Venous Blood Clots Do Not Increase Mortality in Scleroderma Patients, Study Shows

Interstitial Lung Disease Associated with Greater Risk of Lung Cancer in Scleroderma, Study Reports

Nailfold Capillary Damage a Mortality Predictor in Scleroderma, Study Shows

Scleroderma Foundation Among Supporters to Improve Michigan Patients’ Access to Medications

Innate Immune System and MicroRNA Play Crucial Roles in Scleroderma Development, Study Suggests

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