Author Archives: Janet Stewart, MSc

Variability of Pulmonary Hypertension in SSc Patients Demands Tailored Treatments, Study Argues

Considerable differences in features of pulmonary hypertension among people with systemic sclerosis (SSc) markedly affect their survival chances, and treatment approaches given should be tailored accordingly, according to an analysis of patients grouped according to lung disease severity. SSc patients with pulmonary hypertension (PH) but no evidence — or limited…

Focus Group Study Looks at How Patients Often Cope with Scleroderma

An analysis of focus group discussions between patients with systemic sclerosis (SSc), or scleroderma, found that participants coped with their disease in three general ways: by concentrating on solutions to a problem and seeking professional help, managing their emotions, and looking for benefits and adjusting goals to the realities of their…

High Levels of Thioredoxin-1 Restore Normal Skin Tissue in Mice with Systemic Sclerosis, Study Shows

Injecting bone marrow cells designed to produce high levels of thioredoxin 1 (Trx-1) restored skin tissue in mice with systemic sclerosis (SSc), according to Chinese researchers. Their study, “Bone Marrow-Derived Mesenchymal Stem Cells Expressing Thioredoxin 1 Attenuate Bleomycin-Induced Skin Fibrosis and Oxidative Stress in Scleroderma,” appeared in the…