iBio, Inc., a plant-based biotechnology company focused on developing biological therapies for several fibrotic diseases including idiopathic pulmonary fibrosis and systemic sclerosis, recently announced it has received a notification from the European Patent Office stating that the opposition period for the iBio patent 2192172, entitled “System for Expression of…
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Reata Pharmaceuticals, Inc., a biopharmaceutical company based in Irving, Texas, recently announced positive data from the Phase 2 clinical trial LARIAT assessing the company’s candidate product bardoxolone methyl for pulmonary arterial hypertension (PAH). The results were recently presented by Dr. Ronald Oudiz, Director of the Pulmonary Hypertension Center and…
Cytori Therapeutics, Inc., a company focused on therapeutics and devices in the field of regenerative medicine, recently reported it has enrolled and administered treatment to the first patient in its ongoing SCLERADEC-II trial, a late phase, follow-on European study that aims to evaluate the efficacy and safety profile of Cytori…
A recent study identified a novel molecule implicated in the development of skin fibrosis, a serious disease characterized by the inflammation and hardening of skin tissue. The study entitled “The matrix protein Fibulin-5 lies at the interface of tissue stiffness and inflammation in fibrosis” was recently published…
Researchers Identify Potential Genetic Pathways of Systemic Sclerosis-Associated Pulmonary Fibrosis
In a recent study entitled “Molecular network of important genes for systemic sclerosis-related progressive lung fibrosis”, published in the BMC Research Notes journal, a team of researchers from the US and China established the expression levels of crucial genes for Systemic Sclerosis-related progressive pulmonary…
This week at the Scleroderma Foundation of Southern California’s 17th annual “Key to a Cure” gala, Genentech‘s Senior Group Medical Director of Immunology, Dr. Jeffrey Siegel, will receive the honor of the Spirit of Leadership Award. The award is given to prominent individuals who have contributed to the scientific and…
In a recent study entitled “B regulatory cells are decreased and functionally impaired in patients with systemic sclerosis”, researchers report that a specific population of B cells – regulatory B cells – with established functions in immune suppression, have their numbers markedly reduced and functions impaired in systemic…
In a recent study entitled “Difficulties in diagnosis of systemic sclerosis-related interstitial lung disease”, researchers present a case-report of a Caucasian woman and highlight the difficulties in identifying and diagnosing systemic sclerosis-associated with interstitial lung disease. The study was published in the Respirology Case Reports…
A new study recently published in the journal BMC Musculoskeletal Disorders revealed that patients with systemic sclerosis have a reduced incidence of Crohn’s disease in comparison to the general population. The study was performed by a team of researchers at several universities in Taiwan, and is entitled…
In a newly published paper in PLOS one journal entitled “Relationship between Body Mass Composition, Bone Mineral Density, Skin Fibrosis and 25(OH) Vitamin D Serum Levels in Systemic Sclerosis,” researchers from University of Foggia in Italy investigated if skin sclerosis (SSc) could…
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