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Systemic Sclerosis-overlap Syndrome To Be Taken A New Disease Subset

Researchers from the University of Cologne in Germany showed that Systemic sclerosis-overlap Syndrome should be regarded as different separate subset in Systemic sclerosis (SSc) patients. The study entitled “Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis” appeared on…

Clinical Phase I/II Pilot Trial Will Study New Therapy for Systemic Sclerosis

Children’s Hospital Los Angeles is recruiting Refractory Systemic Sclerosis Patients between 8 to 18 years of age for a Phase I/II pilot trial of the drug Campath-1H (ClinicalTrials.gov identifier: NCT01639573) to address whether prolonged administration of the drug can result in immunoablation. Campath-1H is a trade name…

Botulinum Toxin Studied as Therapy for Scleroderma-Associated Raynaud’s Syndrome

Botulinum toxin has been very popular for reducing wrinkles and more recently for treating painful conditions. The toxin may soon have a new use for another medical condition. Johns Hopkins University researchers are studying whether botulinum toxin can provide relief to people suffering from scleroderma-associated Raynaud’s Syndrome. Scleroderma is…

SSc Patients May Improve with Grafts of Their Own Fat

Italian scientists may have identified a way to improve systemic sclerosis (SSc) symptoms with fat grafts. A recent study titled “Autologous Fat Grafting in the Treatment of Fibrotic Perioral Changes in Patients with Systemic Sclerosis” published in the journal Cell Transplantation showed that…

Lung Transplantation Poses Higher Risk for Systemic Sclerosis Patients

Researchers at Columbia University College of Physicians and Surgeons in New York reported that adults with interstitial lung disease (ILD) and systemic sclerosis (SSc) undergoing lung transplantation in the United States are almost 50% more likely to die within one year than people who have lung disease, transplantion but no…

Researchers Explore Prediction of Scleroderma Renal Crisis With Anti-RNAP III

Scientists from the Department of Dermatology at the Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Japan have confirmed that antibodies to a specific enzyme — RNA polymerase III — are associated with scleroderma renal crisis (SRC). RNA polymerase III’s normal function is to convert (transcribe) DNA into RNA. Antibodies to RNA polymerase III are called anti-RNAP…