Sine sclerosis, which is also known as sine scleroderma or systemic sclerosis sine scleroderma (ssSSc), is an extremely rare type of scleroderma.
Unlike “regular” scleroderma, in sine sclerosis the buildup of fibrosis occurs not on the skin but in one or more internal organs, which may also be affected by Raynaud’s phenomenon. This excess of tissue is most common around problem areas like the heart, parts of the respiratory system and the kidneys. That means that this type of scleroderma is much harder to diagnose as it’s not visible to the naked eye.
Look out for signs that are centered around the organs affected, including heartburn, difficulty swallowing, shortness of breath, intestinal problem and kidney problems, among others.
While there’s currently no known treatment for the origin of the disease (the overproduction of collagen), there are several treatments that may help manage the symptoms. Any treatment plan will need to be monitored by a team of specialists.
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