Specific self-reactive antibodies are associated with different symptoms and complications in people with systemic sclerosis (SSc) without overlap syndrome, a study in Brazil shows. For instance, autoantibodies targeting Scl70 or centromere were tied to differences in when the disease starts, how the skin is affected, and the risk of…
Some people with systemic sclerosis (SSc) have autoimmune hepatitis (AIH), a condition marked by liver inflammation caused by self-reactive antibodies, a study in Turkey shows. The study also identified the blood levels of the liver enzyme alanine aminotransferase (ALT) as the most accurate predictor of AIH. “Our findings highlight…
Autologous stem cell transplant (ASCT), a procedure that essentially aims to reset the immune system, was effective for controlling scleroderma in a teenager with severe disease that wasn’t responding well to medications. “ASCT may represent an important therapeutic option, particularly perhaps in patients who develop severe disease at a…
Becoming educated and informed about scleroderma is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your scleroderma journey.
There is no cure for scleroderma yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
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