Researchers have identified a molecular pathway in specific skin cells called keratinocytes that may be involved in inflammation and scarring in scleroderma affecting the skin. According to data from a mouse model of the disease, loss of the protein Med1 in keratinocytes leads to more severe disease, likely by…
Some genetic factors linked to systemic sclerosis (SSc), also called scleroderma, may influence disease susceptibility differently in women and men, according to a new study. Researchers say these findings may help explain why the disease is much more common in women, but often more severe…
Specific self-reactive antibodies are associated with different symptoms and complications in people with systemic sclerosis (SSc) without overlap syndrome, a study in Brazil shows. For instance, autoantibodies targeting Scl70 or centromere were tied to differences in when the disease starts, how the skin is affected, and the risk of…
Becoming educated and informed about scleroderma is a good first step. Here you’ll find general information about the disease, including diagnosis, symptoms, and causes.
It helps to know others have been where you are now. Here’s a collection of our columnists’ words of wisdom to help you along on your scleroderma journey.
There is no cure for scleroderma yet, but here you can find more information about current therapeutic approaches, as well as experimental treatments that are in the pipeline.
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