HMGB1 Protein May Drive Blood Vessel, Tissue Damage in Scleroderma, Study Suggests
A protein involved in inflammation and tissue regrowth — HMGB1 — may be the main driver of blood vessel damage and tissue fibrosis in scleroderma, suggesting its potential as a therapeutic target, according to a study. The study, “Platelet microparticles sustain autophagy-associated activation of neutrophils in…