Nitroglycerin ointment is a nitrate that relaxes blood vessels. The vasodilator is typically used to treat moderate to severe pain caused by chronic anal fissures, but it can also be prescribed to scleroderma patients to help heal skin ulcers caused by Raynaud’s phenomenon.

A study testing nitroglycerin ointment against diltiazem gel  (NCT02801305) as a way of healing digital ulcers in scleroderma is currently recruiting participants. Digital ulcers  are a common complication for scleroderma patients, and the study aims to evaluate the effects of the two treatments on scleroderma digital ulcers over a 10-month course.

Some of the most common side effects of nitroglycerin ointment are dizziness, faintness on standing, headache, and light-headedness.

Scleroderma News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

 

  1. https://www.drugs.com/cdi/nitroglycerin-ointment.html
  2. http://www.mayoclinic.org/diseases-conditions/raynauds-disease/basics/treatment/con-20022916
  3. https://clinicaltrials.gov/ct2/show/NCT02801305