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SSc lung cells show gene activity linked to scarring in study

Cells present along the walls of small blood vessels in the lungs, called pericytes, have distinct gene activity in people with systemic sclerosis (SSc)-associated pulmonary fibrosis (PF), according to a new study. Pericytes from SSc patients showed an increased expression, or activity, of genes involved in lung fibrosis (scarring), blood…

CONQUEST platform trial of SSc-ILD now enrolling patients in US

CONQUEST, a platform clinical trial launched by the Scleroderma Research Foundation (SRF), is now enrolling people with interstitial lung disease associated with systemic scleroderma (SSc-ILD) at centers in the U.S. The study is analyzing two investigational therapies using a master protocol to compare both treatments with a…