News

‘Cool Comedy, Hot Cuisine’ 2022 Fundraiser to Honor Bob Saget

The Scleroderma Research Foundation‘s annual star-studded “Cool Comedy, Hot Cuisine” event will this year honor the late comedian and actor Bob Saget, who spearheaded the fundraiser for three decades. Saget, who died in January, had worked for more than 30 years to promote scleroderma research following the death of his…

APT-101 Lowers Fibrosis, Inflammation in Mouse Model

The investigational oral therapy APT-101 was well tolerated and reduced fibrosis, or scarring, in a mouse model of systemic sclerosis (SSc), according to a recent presentation from the therapy’s developer, Apie Therapeutics. Apie is developing APT-101 to treat interstitial lung disease (ILD), a term that encompasses a group…

Multiple Scleroderma-linked Antibodies Possible in Patients

About 2% of people with scleroderma are positive for more than one disease-associated antibody that targets tissues, causing damaging inflammation, according to a new study. Results suggest that certain antibody combinations may be associated with distinct clinical features. The study, “Combinations of scleroderma hallmark autoantibodies associate…