Oral treatment with vitamin B3 for a couple of weeks may reduce abnormalities in tiny blood vessels of people with scleroderma who have Raynaud’s phenomenon, a small study suggests. After two weeks of supplementation, participants showed more normal and fewer giant blood vessels under the fingernails, although these…
News
John Stamos, the Emmy-nominated actor and producer known for his role on “Full House,” will receive the Bob Saget Legacy Award. The Scleroderma Research Foundation (SRF) gives this award to individuals who have used their voices to raise awareness and support research for scleroderma. Stamos will be honored at…
Treatment guidelines for scleroderma (SSc) have evolved since the turn of the century with advances in scientific understanding and the advent of new therapies. In line with these evolving guidelines, patterns of therapies prescribed to people with SSc have shifted markedly since 2000, according to a new analysis from…
Blood levels of a protein called KL-6 may help identify people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) who are at greater risk of short-term lung function decline, according to a new analysis of data from a Phase 3 clinical trial. Among participants who received a placebo in the…
People with scleroderma (SSc) who don’t show the so-called scleroderma pattern, a common diagnostic finding of small blood vessel damage associated with the condition, may experience a milder course of the disease, an Italian study suggests. About 5% of study participants didn’t show this characteristic pattern at the time…
Scientists at Northwestern University have developed a wireless sensor that may help monitor skin stiffness in conditions such as scleroderma from home. “The great thing about the sensor is it’s small, the potential for home use is tremendous, and for patients who know that they are at risk and…
People living with scleroderma are being invited to take part in a new survey designed to better understand how the chronic autoimmune disease affects their daily lives. The findings may help guide future research and, ultimately, improve patient care. The Scleroderma Health and Resources Survey, launched by the…
Scleroderma is now part of a federal program that aims to help understand underlying mechanisms and develop new treatments and diagnostic targets for autoimmune conditions. The Foundation for the National Institutes of Health (FNIH) has expanded its Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases (AMP AIM) program,…
An investigational off-the-shelf, or readily available, CAR T-cell therapy has shown early signs of effectiveness — with clinical improvements and no serious safety concerns — in the first four people with systemic sclerosis (SSc) treated in an ongoing clinical trial in the U.S. and Europe. That’s according to preliminary…
A clinical trial will study investigational therapies in people at the earliest stages of systemic sclerosis (SSc), before irreversible organ damage has occurred. Contract research organization Indero and the World Scleroderma Foundation (WSF) are partnering on the trial, called WSF SHIELD. It will test multiple investigational therapies in…
Recent Posts
- Vitamin B3 may improve blood vessels in scleroderma-related Raynaud’s
- John Stamos to be honored for longtime support of scleroderma research
- Study maps shift in prescribing patterns as guidelines evolve
- Blood protein may help predict lung decline in scleroderma-related ILD
- Lack of small blood vessel damage patterns may predict milder SSc
- Wireless sensor may help track scleroderma skin changes at home
- New scleroderma survey seeks patient input to guide future research
- Scleroderma added to NIH project targeting autoimmune diseases
- Off-the-shelf cell therapy shows early promise as scleroderma treatment
- Trial to test scleroderma treatments at earliest stages of disease