Patrícia Silva, PhD, director of science content —

Researchers at the University of Colorado Boulder and Tsinghua University in China recently published in the journal Science Advances that a specific small molecule is capable of triggering an immune response, having potential biomedical applications for treating diseases such as Scleroderma. The study is entitled “…

In a recent study published in the journal Arthritis Research & Therapy, a research team from the Yonsei University College of Medicine in Seoul, South Korea found that patients with Raynaud’s phenomenon (RP) met 2013 American College of Rheumatology/European League Against Rheumatism criteria for systemic sclerosis…

The European Commission has granted late stage cell therapy company Cytori Therapeutics, Inc.’s ECCS-50 cellular therapy the designation of orphan medicinal product for the treatment of scleroderma. The decision, which was made due to positive references from the European Medicines Agency’s (EMA) Committee for Orphan Medicinal Products, represents the first time an…

Results from a recent study published in the journal The Egyptian Rheumatologist provide new evidence of inner ear involvement in Systemic sclerosis (SSc) causing audiovestibular abnormalities. Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by fibrosis mainly in the skin, vasculopathy with…

A recent Case Report entitled “Posterior Reversible Encephalopathy Syndrome as Presenting Form of Very Early Systemic Sclerosis,” describes a rare case of a patient with Posterior Reversible Encephalopathy Syndrome (PRES) caused by arterial hypertension and very early systemic sclerosis (SSc). The report is published in…

Researchers at Centro Universitário Augusto Motta and Hospital Federal de Bonsucesso in Rio de Janeiro, Brazil recently discovered that muscle strength in the lower limbs of patients with systemic sclerosis influences the patient’s functional capacity and quality of life. The study is entitled “Lower…

A recent study published in the journal PLOS One reports the results of a comprehensive clinical assessment review in patients with Systemic sclerosis and lung cancer. Systemic sclerosis (SSc) is a connective tissue disorder characterized by immune dysregulation and accumulation of extracellular matrix constituents resulting in…

A case study of a patient with Scleroderma recently published in the journal JAAD Case Reports reports the clinical outcomes of treatment with HDAC (Histone deacetylase inhibition) with divalproex sodium. Scleroderma is a complex autoimmune connective tissue disease, and although the causes remain unclear, research suggests that transforming growth…

The Assistance Publique – Hôpitaux de Paris is collaborating with Actelion Pharmaceutics on a study testing the efficacy, safety and tolerability of bosentan in patients with scleroderma renal crisis on renal function (ClinicalTrials.gov Identifier: NCT01241383). Systemic sclerosis (SSc) is an auto-immune disorder that causes excessive collagen deposition,…

A recent study published in the journal Arthritis Research & Therapy analyzed different prediction algorithms for the efficient diagnosis of pulmonary arterial hypertension (PAH) in patients with systemic sclerosis. The study is entitled “A comparison of the predictive accuracy of three screening models…