Author Archives: Margarida Azevedo, MSc

Scleroderma Research and Clinical Study Guidelines Drawn from Agreements at SSc World Congress

In a new article, a multidisciplinary team of international researchers summarized key points and deliberations regarding basic, clinical, and novel therapeutic research made at a World Scleroderma Foundation three-day meeting that gathered senior and junior investigators across research areas, as well as a patient spokesperson. The report’s main goals were to…

Biopharma Company That’s Developing Potential Therapy for Systemic Sclerosis Is Recognized for Innovative Approach at 4th World Congress

The organizing committee of the 4th Systemic Sclerosis World Congress recently held in Lisbon, Portugal on Feb. 18-20 recognized Inventiva, a biopharmaceutical company focused on the development of treatments for fibrosis, oncology, and orphan diseases, for its innovative approach in the development of its lead drug candidate, IVA337, a promising…

Research of Lung Fibrosis in Scleroderma Reveals High Levels of Antibodies That Correlate with Disease Progression

Researchers at Germany’s University of Luebeck and Charité University recently presented a study where they reported that circulating antibodies against specific chemokine (small proteins with an important role in the immune system) receptors exist in higher levels in patients with systemic sclerosis, and these antibodies correlate with disease progression and clinical…

Systemic Sclerosis Research Indicates Estrogen May Play Positive Role, Potentially Leading to Treatments

Researchers at Paris Descartes University, France, recently presented the results of a study investigating the effects of estrogen in the development of experimental dermal fibrosis and on the response of profibrotic cells to the major fibrosis cytokine-transforming growth factor (TGF)-β. The presentation, “Estrogens Inhibit the Profibrotic Effects of…

Systemic Sclerosis Pathogenesis Appears Linked to Changes in Endothelial Cells, Researcher Tells SSc World Congress 2016

Scientists from the University of Florence, Italy, presented a study investigating the participation of the Endothelial-to-Mesenchymal transition (EndoMT) process in the pathogenesis of systemic sclerosis (SSc) at the 4th Systemic Sclerosis World Congress in Lisbon, Portugal, that concluded Feb. 20, 2016. SSc is a chronic connective tissue disease…