José holds a PhD in Neuroscience from Universidade of Porto, in Portugal. He has also studied Biochemistry at Universidade do Porto and was a postdoctoral associate at Weill Cornell Medicine, in New York, and at The University of Western Ontario in London, Ontario, Canada. His work has ranged from the association of central cardiovascular and pain control to the neurobiological basis of hypertension, and the molecular pathways driving Alzheimer’s disease.
A Phase 2a clinical trial will test the investigational therapy GLPG1690 in patients with diffuse cutaneous scleroderma. The double-blind, placebo-controlled Phase 2a study, called NOVESA (NCT03798366), will evaluate the ... Read more
Mutations in the FAM111B gene are rare in scleroderma patients and not associated with disease development, according to new research. This finding was reported in the study, “Mutations of FAM111B gene ... Read more
Patients with scleroderma and pulmonary arterial hypertension (PAH) have increased levels of two serum proteins, midkine (MDK) and follistatin-like 3 (FSTL3), according to a new study. The finding indicates ... Read more
Patients with both scleroderma and systemic lupus erythematosus (SLE) are younger at diagnosis, are more often women, and have less skin manifestations, but most importantly, show similar survival rates ... Read more
Treatment with Opsumit (macitentan) and Esbriet (pirfenidone) provided stable improvements in a scleroderma patient with interstitial pneumonia and borderline pulmonary arterial hypertension (PAH), according to a Japanese case report. The ... Read more
The occurrence of blood clots in the veins of scleroderma patients is rare and does not change patients’ survival rates, a new Canadian study shows. Still, researchers see a need ... Read more