What Is Sine Sclerosis?

Sine scleroderma is the term used when there is no skin involvement with the disease. (“Sine” is latin for “without.”) Typically, scleroderma patients experience problems with the skin as the disease causes the body to overproduce collagen. However, in sine scleroderma, internal parts of the body can be affected with fibrosis but the skin is left unaffected.

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Because there are no external signs of the disease, sine sclerosis can be extremely difficult to diagnose compared to the usual form of the condition. Patients with sine sclerosis will be affected by Raynaud’s phenomenon and will have fibrosis in one or more internal organs, most commonly the esophagus, lungs, kidneys, and heart. Find out more about sine scleroderma here. 

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Scleroderma News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.