What Is Sine Sclerosis?
Sine scleroderma is the term used when there is no skin involvement with the disease. (“Sine” is latin for “without.”) Typically, scleroderma patients experience problems with the skin as the disease causes the body to overproduce collagen. However, in sine scleroderma, internal parts of the body can be affected with fibrosis but the skin is left unaffected.
Because there are no external signs of the disease, sine sclerosis can be extremely difficult to diagnose compared to the usual form of the condition. Patients with sine sclerosis will be affected by Raynaud’s phenomenon and will have fibrosis in one or more internal organs, most commonly the esophagus, lungs, kidneys, and heart. Find out more about sine scleroderma here.
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