Scleroderma is a systemic autoimmune disease that causes hardening of the skin and connective tissues. The disease mostly affects women ages 30-50, but children and men can also get it. There is known cause for scleroderma yet — but scientists are looking at the following factors for potential higher risks for the disease, according to the Scleroderma Research Foundation:
Although the disease doesn’t tend to run in families, some researchers think certain people may have a genetic predisposition for the condition. However, this doesn’t mean that a scleroderma patient will go on to have children with the disease.