A Phase 3 trial testing iloprost, known as CIVI030, for the treatment of Raynaud’s phenomenon due to scleroderma has resumed patient enrollment, according to the therapy’s developer, CiVi Biopharma. The trial (NCT04040322), named AURORA and sponsored by Civi’s subsidiary Eicos Sciences, launched…
News
Same But Different, a nonprofit U.K. group that uses art for social change, is inviting people to choose their favorite photographs in a calendar contest to heighten awareness of rare diseases, including amyotrophic lateral sclerosis (ALS). The organization’s panel of judges has pared the number of contest submissions…
Following the onset of the COVID-19 pandemic, people with scleroderma experienced substantial increases in anxiety, but not depression, a new study has found. Results also show that older patients and those with greater financial resources experienced smaller increases in anxiety. The study, “Changes in mental health…
A new computer software, called Capillary.io, uses artificial intelligence (AI) to aid in diagnosing scleroderma at early disease stages. The tool, developed in partnership with the Sociedad Española de Medicina Interna (SEMI), was designed specifically to improve a non-invasive, highly sensitive and inexpensive technique — called nailfold capillaroscopy — used by…
A protein known as TL1A drives lung fibrosis, or scarring, in scleroderma, a new study suggests. The findings suggest that blocking TL1A could be an effective therapeutic strategy in scleroderma and other conditions characterized by lung fibrosis, including severe asthma, and idiopathic pulmonary fibrosis. Titled, “…
Muscular involvement is linked with more severe symptoms in people with scleroderma, affecting heart, lungs and the digestive system, a study from China reports. These patients are likely to have a worse disease prognosis and poorer survival, its data show. The study “Myopathy is a Risk Factor for…
Bob Saget will return to host the 34th annual Cool Comedy – Hot Cuisine fundraiser, benefiting the Scleroderma Research Foundation (SRF), on Sunday, Oct. 18. The comedian will be joined by celebrity chef and restaurateur Susan Feniger as co-host of the now online event.
Rituximab, in combination with CellCept (mycophenolate mofetil), reverses the decline in lung function in people with interstitial lung disease (ILD) associated with scleroderma (SSc) who did not respond to immunosuppressant therapies, a study suggested. The study, “…
Detailed characteristics of 12 cases of lung cancer in people with scleroderma were described in a new study. Notably, all patients were women and most had interstitial lung disease (ILD). The study, “Clinicopathological characteristics of lung cancer in patients with systemic sclerosis,” was published…
Treatment with lenabasum failed to outperform a placebo when given as an add-on to standard immunosuppressants in adults with diffuse cutaneous scleroderma (dcSSc), top-line data from a Phase 3 trial show. Participants given a placebo on top of immunosuppressants experienced an unprecedented improvement, Corbus Pharmaceuticals said in…
Recent Posts
- New study flags existing medications as possible scleroderma treatments
- Anti-CD146 antibodies may signal occupational exposure in SSc: Study
- New SSc drug safely cuts Raynaud’s attack duration, eases symptoms
- Carbon dioxide hand baths may help in SSc-related Raynaud’s, study finds
- More SSc-ILD patients receive early treatment, new study finds
- CD13 levels elevated in scleroderma, but biomarker value unclear
- New lab findings support development of stem cell treatments for SSc-ILD
- Type of immune cell may be key driver of scleroderma scarring: Study
- Abnormal fatty acid metabolism may play role in scleroderma: Analysis
- Cosmetic laser therapy could be repurposed for localized scleroderma