News

UVA1 Phototherapy Appears to Ease Lesions in Localized Scleroderma

UVA1 phototherapy, a form of treatment that uses light for skin disorders, helps ease skin lesions in people with localized scleroderma by regulating certain genes responsible for inflammation and scarring, a study has found. The study, “Clinical and laboratory characterization of patients with localized scleroderma and response to…

Organoid Treatment Lowers Inflammation, Fibrosis in Mice

Treatment with stem cells grown into a skin-like structure called an organoid reduced inflammation and fibrosis (scarring) in a mouse model of localized scleroderma, a new study found. The study, “Application of an iPSC-Derived Organoid Model for Localized Scleroderma Therapy,” was published in Advanced Science.

Ultrasound Plus Manual Therapy Helps in Healing Digital Ulcers

A combination of ultrasound and therapy that includes joint manipulation and massage improved hand function and ulcer wound healing in a small group of systemic sclerosis (SSc) patients with skin involvement, a study reported. “Therapeutic [ultrasound ] combined with manual therapy should be used as additional intervention to manage…

Worse Organ Damage Likely for Older Men With Diffuse SSc: Study

Several clinical characteristics in people with systemic sclerosis (SSc) — specifically, being male, older age, diffuse SSc forms, and inflammation — were associated with a greater accumulation of organ damage over time in a recent study. The level of damage accumulation, called a damage trajectory, also correlated with mortality…