Posts by: Santiago Gisler

News

The mortality rate among people with systemic sclerosis (SSc) has not changed over time and continues to be high, according to a combined analysis of a French multicenter cohort ... Read more

April 22, 2019April 22, 2019

Rituximab Safe, Eases Skin Fibrosis in Systemic Sclerosis Patients, Study Suggests

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Rituximab, an immunosuppressant antibody, alleviates skin fibrosis in patients with systemic sclerosis (SSc) and was also found to be generally safe, according to a study. The study, “Outcomes of ... Read more

April 1, 2019April 1, 2019

Skin Fibrosis Scores Can Be Surrogate Marker for dcSSc Severity, Study Finds

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Progressive skin fibrosis within one year increases the risk of lung function decline and mortality in patients with diffuse cutaneous systemic scleroderma (dcSSc), a large-scale observational study found. The finding ... Read more

March 21, 2019March 21, 2019

Nintedanib Submitted for Regulatory Approval to Treat SSc-ILD in US and Europe

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Boehringer Ingelheim has submitted its proprietary therapy nintedanib to the U.S. Food and Drug Administration and the European Medicines Agency for regulatory approval to treat systemic sclerosis (SSc)-associated interstitial lung disease ... Read more

March 19, 2019March 19, 2019

Poor SSc-PH-ILD Prognosis May be Linked to Pulmonary Veno-occlusive Disease

News

A high prevalence of pulmonary veno-occlusive disease (PVOD) in systemic sclerosis (SSc) patients with pulmonary hypertension associated with interstitial lung disease may explain the poor prognosis observed in this ... Read more

February 28, 2019February 28, 2019

SSc Patients’ Health-related Quality of Life Worse Than Those With Other Rheumatoid Diseases, Study Finds

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Patients with systemic sclerosis (SSc) have reduced health-related quality of life compared with other systemic rheumatoid diseases, a new study shows. A significant association between skin thickness scores and ... Read more

February 7, 2019February 7, 2019

sE-selectin, sIL-2R Levels Are Potential Markers of Localized Scleroderma Activity

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Serum levels of E-selectin (sE-selectin) and soluble interleukin-2 receptor (sIL-2R) are potential prognostic markers of progression and severity in localized scleroderma, according to a recent study. The study, “The ... Read more

February 5, 2019February 5, 2019

SSc Patients Show Improvements After CD34-selected Stem Cell Transplant, Study Reports

News

Systemic sclerosis (SSc) patients showed reduced skin thickness and improved lung function after a hematopoietic stem cell transplant (HSCT) using blood progenitor cells positive for the CD34 marker, a ... Read more

December 13, 2018December 13, 2018

Pacemaker May Be Necessary in SSc Patients With Complete Heart Block, Case Report Suggests

News

Pacemaker implantation in systemic sclerosis (SSc) patients with secondary complete heart block (CHB) may be a required procedure to avoid clinical complications, according to recent case report. The case ... Read more

December 4, 2018December 4, 2018

Pulmonary Arterial Hypertension Is Main Cause of Death in SSc Patients, According to Study

News

Pulmonary arterial hypertension (PAH) is the main cause of death among systemic sclerosis (SSc) patients, according to a recent Chinese cohort study. Researchers found SSc-related clinical features that associate ... Read more