collagen

October 5, 2017

10 Parts of the Body Affected by Scleroderma

Scleroderma or systemic sclerosis (SSc) is a rare autoimmune disease whereby the body produces too much collagen. The symptoms a person can present are widespread and many different parts of ... Read more

October 5, 2017October 5, 2017

Innate Immune System and MicroRNA Play Crucial Roles in Scleroderma Development, Study Suggests

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The innate immune system and small RNA molecules known as microRNA are key factors in the development of scleroderma, according to a study based on previously published research. The ... Read more

October 3, 2017October 3, 2017

HIV Therapy Viracept May Benefit Systemic Sclerosis Patients, Mouse Study Shows

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Viracept (nelfinavir mesylate, NFV), an antiretroviral drug approved as a therapy against the human immunodeficiency virus (HIV), could be beneficial in the treatment of systemic sclerosis (SSc), a study ... Read more

June 7, 2017

This 10-Year-Old Refuses to Let Scleroderma Get the Best of Her

Ten-year-old Grace began experiencing symptoms of scleroderma in 2015 when she and her family were living in China. Grace was having a hard time brushing her teeth as she couldn’t ... Read more

May 5, 2017

How Scleroderma Can Affect Your Lungs

Scleroderma is an autoimmune disease that occurs when the body overproduces collagen. This collagen can appear in any of the body’s organs, including the lungs. MORE: Six warning signs you may ... Read more

November 10, 2016February 24, 2017

10 Parts of the Body Affected by Scleroderma

April 28, 2016April 28, 2016

FDA Grants Orphan Drug Designation to Fibrocell’s FCX-013, a Gene Therapy for Localized Scleroderma

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The U.S. Food and Drug Administration (FDA) has designated a potential gene therapy for localized scleroderma, FCX-013 by Fibrocell Science, an orphan drug to help advance its development and testing. Fibroblasts, the basis of Fibrocell’s ... Read more

February 9, 2016February 9, 2016

Potential Scleroderma Gene Therapy Moving into Preclinical Dosing Study, Fibrocell Reports

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Fibrocell Science, Inc., recently highlighted the latest advancements in its pipeline of products focused on autologous cell and gene therapy treatments for several conditions, including scleroderma. The company’s autologous fibroblast technology uses ... Read more

November 3, 2015November 3, 2015

Systemic Sclerosis Associated with Alterations in Sub-Populations of B Cells

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In a new study entitled “Systemic Sclerosis Patients Present Alterations in the Expression of Molecules Involved in B-Cell Regulation,” a team of researchers investigated whether patients with systemic sclerosis ... Read more

October 1, 2015October 9, 2015

Rescuing Regulatory B cells Function May Be A New Therapeutics Strategy for Systemic Sclerosis

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In a recent study entitled “B regulatory cells are decreased and functionally impaired in patients with systemic sclerosis”, researchers report that a specific population of B cells – regulatory B ... Read more

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