News

Researchers Evaluate the Effect of Ambrisentan on Digital Blood Flow in Patients with Systemic Sclerosis using Laser Doppler Perfusion Imaging

Researchers from the Hunter Holmes McGuire VA Medical Center, Richmond, VA, and the Department of Rheumatic and Immunologic Diseases, Orthopedics and Rheumatology Institute, Cleveland Clinic, OH, have recently released results from a clinical trial that evaluated the use of ambrisentan, a selective endothelin type A receptor antagonist,…

Pivotal Scleroderma STAR Trial Expansion Approved By the FDA

Cytori Therapeutics, Inc. recently announced an FDA approval that will allow them to expand the number of sites in the United States from 12 to 20 centers where the company’s Scleroderma clinical trials are currently being conducted. The STAR study was approved by the FDA in January 2015 as an 80-patient…

Cytori Receives Positive European Opinion on Scleroderma Orphan Drug Status

Cytori Therapeutics, Inc. recently announced that the European Medicines Agency’s Committee for Orphan Medicinal Products (COMP) has given a positive opinion concerning Cytori’s submission for an orphan drug designation for ECCS-50, the company’s experimental Scleroderma therapeutic, which is based on stromal vascular fraction cells, from adipose tissue and derived from Celution® System,…

Clinical Trial is Testing Stem Cells in Scleroderma

Richard Burt, MD, of Northwestern University is looking to harness the power of autologous, patient-derived stem cells for the treatment of systemic sclerosis. His previous work in a clinical trial with scleroderma motivated a new phase 3 clinical trial, entitled “…

Scleroderma Damage in Hands Better Assessed with Ultrasonographic Scans

New research on musculoskeletal ultrasound (MSUS) hand features in systemic sclerosis (SSc) or scleroderma and rheumatoid arthritis (RA) entitled “A comparative study between ultrasonographic hand features in systemic sclerosis and rheumatoid arthritis patients: Relation to disease activity, clinical and radiological findings” was recently published in the…