How Can CellCept Help Scleroderma Patients?


CellCept is a prescription drug made by Genentech that’s primarily used by patients who have had a liver, kidney or heart transplant. Used in conjunction with other medications like corticosteroids and cyclosporines, CellCept (or mycophenolate mofetil) helps to prevent the body’s immune system from rejecting the transplanted organ.

MORE: Many scleroderma patients needing kidney transplants do well.

CellCept is available in three different forms — capsule, tablet and oral suspension — and can be used for both children and adults.

However, CellCept could soon be used for other areas of treatment as well as organ transplants. Recent clinical trials for CellCept have found that it can also be effective at reducing skin thickening in scleroderma patients. A trial with 300 adults using CellCept over seven years found that skin thickening had been considerably reduced compared to participants on the trial who were given a placebo. Find out more about this study here.

In addition, two separate clinical trials have found that CellCept may be a useful treatment for scleroderma-related lung disease. One clinical trial found that CellCept helped to slow down lung decline, particularly in the first year of treatment. A two-year trial found that CellCept helped to improve lung function with better gas exchange and less shortness of breath in scleroderma patients with lung disease, the drug also improved skin disease compared to those taking a placebo. Find out more about this study here.

MORE: Comparison of CellCept and Cytoxan for scleroderma lung fibrosis found both equally effective.

Scleroderma News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.

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  1. Michele says:

    I have been taking CellCeptnow for close to 7 years. I have noticed that my skin is softer. And I have interstial lung disease and they have not gotten any worse.

    • Karen Lynne Matthews says:


      I sometimes have stomach upset and regurgitate after taking my dosages of CellCept. My issue is the 2nd dose in the evening is taken around dinner time. Often times I can not eat because it should be taken without food. When I take it with food, I get sick.

  2. Barb Ferguson says:

    I have been taking Cellcept for over 3 years now. It has allowed me to resume a normal life. Scleroderma had pretty much taken over and now I’m back to a new normal life after SSc diagnosis. I would suggest to every SSc patient to give it a chance.

    • Kiki says:

      My partner just started taking it this year. He is slightly improved from this time last year when he was bedridden from the scleroderma fatigue and issues with his hands. He’s now up and about walking the dogs and such, but he hasn’t been able to return to work because he cannot use his hands. When you say “resume a normal life,” do you mean back to to prescleroderma levels of activity or do you have a “new normal”?

  3. I just started taking Cellcept for Scleroderma o meant have to have a blood test every 2 weeks Im up to 3 500ml tablets a day In meant to go up to 6 a day I pray in helps and side effects are ok I’ll keep u informed

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