SSc Therapies for Digital Ulcers

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Digital ulcers, or open sores on the fingers and toes that don’t heal, are common complications of systemic sclerosis. Approximately 30% of patients with systemic sclerosis have digital ulcers, most commonly on the fingertips or on the elbows due to taut skin or trauma. These painful sores can lead to impaired hand function, making digital ulcers a prominent complication for patients to manage.

Despite the prominence of digital ulcers in systemic sclerosis patients, there are no approved medications indicated to treat this uncomfortable symptom. As reviewed by “Optimal Management of Digital Ulcers in Systemic Sclerosis,” in the journal Therapeutics and Clinical Risk Management, therapeutic options are designed to prevent or reduce the burden of digital ulcerations in patients with systemic sclerosis. They fall into three categories: nonpharmacologic, pharmacologic, and surgical.

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